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Higher education - University degrees
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The first higher education courses in blood transfusion in France were delivered
in 1975 by the INTS. A decree implemented in 1976 indeed set forth the DUTS (Higher
Degree in Blood Transfusion) as a joint diploma from Pierre et Marie Curie University
and the "French National Centre of Blood Transfusion" which became the INTS in 1994.
The INTS pursues its initial teaching assignment in collaboration with several universities.
More specifically, these universities, in conjunction with the INTS, offer a Higher
integrated curriculum in blood transfusion (CIUTS).
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Initial curricula in blood transfusion implemented by these Universities :
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-
René Descartes - Paris V
-
Pierre et Marie Curie - Paris VI
-
Denis Diderot - Paris VII
-
Jules Verne – Amiens
These curricula are delivered in collaboration with the teachers of the previously
quoted universities, and those from Paris XI – Paris XII – Paris XIII - Bordeaux
II - Lille II – Nantes – Rennes I – Saint Etienne – Strasbourg– Versailles Universities
as well.
Also in collaboration with teachers from the following associated structures : Ecole
d’Application du Service de Santé des Armées (Administration school for the healthcare
of armed forces) – Centre de Transfusion Sanguine des Armées (Blood transfusion
centre of armed forces)– Ecole des Hautes Etudes en Santé Publique (School for higher
public healthcare) – Agence Française de Sécurité des Produits de Santé (French
agency for health product safety) – Institut de Veille Sanitaire (National institute
for public health surveillance) – Laboratoire Français du Fractionnement et des
Biotechnologies (French laboratory for fractionation and biotechnologies) – Assistance
Publique Hôpitaux de Paris (Public welfare Paris hospitals) – Assistance Publique
Hôpitaux de Marseille (Public welfare Marseille hospitals) - Direction Générale
de la Santé (National health executive) – Institut National de la Santé et de la
Recherche Médicale (National institute for health and medical research) – Etablissement
Français du Sang (French blood establishment) – Agences Régionales de Santé (Regional
health and welfare bureaux in Auvergne, Bretagne, Franche-Comté, Ile de France,
Languedoc-Roussillon, Lorraine, Nord, Pas de Calais, Normandie, PACA, Pays de Loire,
Picardie).
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This curriculum is composed of 25 modules (M1 to M25)
as follows:
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Higher degrees
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Modules
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Transfusion Technology Capacity (CTT)
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1,2,3,4,5,6,7,8,9,10,11,12,13,
14,16,17,18,19,20,21,23,24,25
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Specialized degree in hæmobiology-transfusion (DESC)
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1 to 25
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Blood Transfusion University Degree (DUTS)
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1 to 25
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Inter-university degree for ‘therapeutic principles in transfusion technology’ (D3T)
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1,3,8,10,11
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University degree for quality and safety of blood components (DUQSPS)
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1 to 21
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University degree for Continuous Improvement and Quality implementation (DFQ)
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4 specific modules
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The INTS is involved and responsible for the pedagogical and logistic organization
of the curricula it delivers.
Diplomas can be picked up directly at the University.
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C.I.U.T.S.
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The CIUTS (Higher integrated curriculum in blood transfusion) is unique in Europe.
It is delivered by the INTS (French national institute of blood transfusion) in
collaboration with different universities.
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This curriculum is composed of 25 modules. According to his/her objectives and the
number of modules he/she is registered in, the student is likely to apply to one
of the following higher degrees:
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D.U.T.S. – Blood Transfusion University Degree
Coordinator : Prof. Philippe ROUGER (Paris VI University)
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This Doctorate-level university degree is delivered by the Paris VI University.
Courses are coordinated by the INTS and are meant for future executives, MDs, PharmDs
and scientists from the EFS (French Blood Establishment) or associated laboratories.
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C.T.T. – Transfusion Technology Capacity
Coordinator : Prof. Philippe ROUGER (Paris VI University)
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This national degree allows MDs, non resident and consequently not having passed
the DES or DESC, to bear responsibilities in transfusion, in blood transfusion establishments
or hospitals.
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D.E.S.C. – Specialized degree in Haemobiology-Transfusion
Coordinator : Prof. Philippe ROUGER (Paris VI University)
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This national degree is a vocational curriculum meant for residents or former residents.
The DESC curriculum encompasses the DUTS. Duration : 2 years, of which 1 as a resident.
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D.3T. - Inter-university degree for ‘therapeutic principles in transfusion technology’
Coordinators : Prof. Philippe ROUGER (Paris VI University), Prof. Jean-Luc WAUTIER
(Paris VII University), Prof. Jean-Jacques LEFRERE (Amiens University)
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This degree has been implemented in 2004-2005, in substitution to the DUMT (University
Degree of Transfusion Medicine), in conjunction between Paris VI, Paris VII and
Picardie Jules Verne – Amiens Universities. It is meant for the MDs or PharmDs in
charge of a blood repository or responsible for Haemovigilance inside their establishment.
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D.F.Q. - University degree for Continuous Improvement and Quality implementation
Coordinator: Dr. François TRAPADOUX
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Initiated since the 2010-2011 university new term, this 140-hour graduating curriculum
is meant for biologists, quality managers or their staff, wishing to get trained
and reach for a practical experience of the laboratory-implemented ISO 19011, 15189,
17025, 22870 accreditation, securing its permanence thanks to technical and quality
evaluations as imposed by the regulations in force and the COFRAC (French accreditation
institution) policies.
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Applications to register (cover letter + detailed resume) should be sent
to :
Professor Philippe ROUGER - INTS – 6 rue Alexandre Cabanel – F-75739 Paris Cedex
15
Information : Secretariat – Education & Training Dept. : +33 (0)1 44 49 30 23
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D.U.Q.S.P.S. - University degree for quality and safety of blood components
Coordinator : Prof. Dominique VIGNON (Paris V University)
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Meant for MDs and PharmDs, this curriculum aims at teaching not only the bases in
transfusion safety and quality but also an in-depth knowledge in blood derivatives.
It is set up by Paris V University – Prof. Dominique Vignon,
d.vignon@hopital-foch.org
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CIUTS : 2010 – 2011 syllabus
The following chart displays modules as part of the academic curriculum of each
degree.
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Oct. 22, 2010
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Module 1 (M1)
CTT/D3Ti/DESC/DUTS/DUQSPS
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Blood transfusion organization in France and in Europe
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09h00-11h30
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Organization of the French transfusion and role of the different instances
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Prof. Ph. Rouger
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11h30-13h00
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Organization in Europe - Social-economy in blood transfusion
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Prof. Ph. Rouger
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14h00-15h30
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Implementation of European regulations in French blood establishments and healthcare
facilities
|
Dr. M. Carlier
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15h30-17h00
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Stakes of HPST law in transfusion safety
|
Dr. J.J. Cabaud
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TOP
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Oct. 29, 2010
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Physiology of blood cells
Module 2 (M2)
CTT/DESC/DUTS/DUQSPS
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Hematopoiesis, erythrocyte physiology and basic immunology
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09h00-11h00
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Hematopoïesis
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Dr. F. Norol
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11h00-12h30
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Erythrocyte physiology
|
Dr. M. Rossignol
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14h00-17h00
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Basic immunology : antigens and antibodies
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Dr. F. Cognasse
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TOP
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Nov. 5, 2010
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Immuno-Hematology (1)
Module 3 (M3)
CTT/D3Ti/DESC/DUTS/DUQSPS
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Erythrocyte blood groups : structure and roles
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09h00-12h30
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ABO system and associates
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Dr. V. Van Huffel
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14h00-17h00
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RH, Kell, Duffy, Kidd, MNS… systems
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Dr. V. Van Huffel
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17h00-18h30
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The allo-immunization
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Dr. T. Peyrard
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TOP
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Nov. 12, 2010
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Immuno-Hematology (2)
Module 4 (M4)
CTT/DESC/DUTS/DUQSPS
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Immuno-Hematology Techniques and investigations
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09h00-13h00
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Immuno-Hematology techniques : clusters - RAI - TCD - Elution - Compatibility and
interpretation
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Dr. B.N. Pham
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14h00-15h30
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What to do when a transfusion haemolytic accident occurs in a laboratory
|
Dr. C. Krause
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15h30-17h00
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Autoimmune hemolytic anemia – What treatment should be envisaged ?
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Dr. C. Krause
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TOP
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Nov. 19, 2010
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Immuno-Hematology (3)
Module 5 (M5)
CTT/DESC/DUTS/DUQSPS
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Molecular biology & Immuno-hematology
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09h00-13h00
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Molecular approach of blood groups : structure and roles
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J.P. Cartron
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14h00-15h30
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Erythrocyte blood groups : What’s up ?
|
Dr. B.N. Pham
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15h30-18h00
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Hemolytic disease of the new-born
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Drs. A. Mailloux &
Y. Brossard
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TOP
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Nov. 26, 2010
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Donation : medical aspects
Module 6 (M6)
CTT/DESC/DUTS/DUQSPS
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09h00-11h00
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Interview, questionnaire, information
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Dr. B. Pelletier
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11h00-13h00
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Medical examination, adverse reactions
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Dr. B. Pelletier
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14h00-15h30
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Psycho-sociological approach of the donor
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Dr. B. Danic
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15h30-16h30
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Sociological aspects of blood donation in France : Ethics and regulations
|
Dr. B. Danic
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16h30-18h00
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Epidemiology of infectious reagents and residual risk
|
Dr. J. Pillonel
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TOP
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Dec. 3, 2010
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Blood collection – Preparation of labile blood products (1)
Module 7 (M7)
CTT/DESC/DUTS/DUQSPS
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09h00-11h00
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Aphaeresis techniques
|
Dr. C. Coffe
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11h00-13h00
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Donation types, including autologous donation
|
Dr. G. Woimant
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14h00-16h00
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Preparation of cell labile blood products
|
Dr. R. Tardivel
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16h00-18h00
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Plasma components & indications (raw material included)
|
Prof. M. Joussemet
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TOP
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Dec. 17, 2010
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Preparation of labile blood products (2) – Distribution & delivery (1)
Module 8 (M8)
CTT/D3TI/DESC/DUTS/DUQSPS
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Labile blood products
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09h00-13h00
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Quality control and conservation of labile blood products : red cell and platelet
concentrates, therapeutic plasma
|
Dr. S. Bégué
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Distribution
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14h00-15h30
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Distribution – Delivery of labile blood products
|
Dr. A. François
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15h30-17h00
|
Practical aspects
|
Dr. A. François
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17h00-18h30
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Final bedside controls
|
Dr. C.Trophilme
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TOP
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Jan. 7, 2011
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Preparation of labile blood products (3) – Blood-transmissible diseases (1)
Module 9 (M9)
CTT/DESC/DUTS/DUQSPS
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09h00-10h00
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Preparation of labile blood products and prevention of certain transfusion adverse
reactions (non-hemolytic fever, allergy, GVH)
|
Dr. R. Tardivel
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10h00-12h00
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Prevention against blood-transmissible CMV and B19 Parvovirus
|
Prof. D. Vignon
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12h00-13h00
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Pathogen reduction in therapeutic plasma
|
Dr. Y. Piquet
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14h00-15h00
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Platelet physiology
|
Prof. J.P. Cazenave
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15h00-16h00
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Pathogen reduction in platelet concentrates
|
Prof. J.P. Cazenave
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16h00-17h00
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Pathogen reduction in red cell concentrates
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Prof. J.P. Cazenave
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TOP
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Jan. 14, 2011
|
Blood-transmissible infectious agents (2)
Module 10 (M10)
CTT/D3Ti/DESC/DUTS/DUQSPS
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09h00-11h00
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Blood-transmissible parasite diseases : Paludism, Chagas disease, etc ...
|
Dr. M. Thellier
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13h00-14h30
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Bacterian risk and prevention
|
Dr. P. Morel
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14h30-16h00
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Hepatites virus
|
Dr. S. Laperche
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16h00-18h00
|
Retrovirus – HTLV
|
Dr. S. Laperche
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TOP
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Jan. 21, 2011
|
Blood-transmissible infectious agents (3)
Distribution & delivery (2)
Module 11 (M11)
CTT/D3TI/DESC/DUTS/DUQSPS
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Blood-transmissible diseases
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09h00-13h00
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Emerging pathogens and ATNC (non-conventional transmissible viruslike agents)
|
Prof. J.J. Lefrère
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Delivery of labile blood products
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14h00-16h00
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Transfusion of rare phenotypes. What is the role of the CNRGS ?
|
Dr. T. Peyrard
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16h00-18h00
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Transfusional advice
|
Dr. A. François
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TOP
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Jan. 28, 2011
|
Biological qualification of donations - Automation
Module 12 (M12)
CTT / DESC/DUTS
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Automation
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9h00-13h00
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Automation and IT aspects in transfusion
|
D. Dernis
J.P. Becquart
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Biological qualification of donations
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14h00-15h00
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Organization
|
Dr. M.H. Elghouzzi
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15h00-16h30
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Serological techniques
|
Dr. M.H. Elghouzzi
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16h30-18h00
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VGS (Viral Genomic Screening)
|
Dr. M.H. Elghouzzi
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TOP
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Feb. 4, 2011
|
Quality
Module 13 (M13)
CTT/DESC/DUTS/DUQSPS
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09h00-12h30
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Curriculum : pending
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14h00-16h00
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16h00-17h00
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TOP
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Feb. 11, 2011
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Blood derivatives
Module 14 (M14)
CTT/DESC/DUTS/DUQSPS
|
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Plasma fractionation
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09h00-11h00
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Human plasma fractionation : bases
|
Dr. J.J. Huart
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11h00-12h30
|
Production of blood derivatives
|
Dr. J.J. Huart
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14h00-16h30
|
Indications of human immunoglobulins
|
Prof. L. Mouthon
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16h30-18h00
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Albumin indication
|
Dr. T. Rackelboom
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TOP
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Feb. 18, 2011
|
Hemostasis
Module 15 (M15)
DESC/DUTS/DUQSPS
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09h00-13h00
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Blood derivatives : Factor VIII, Factor IX, Factor Willebrand and others : preparation
and use
|
Dr. Ch. Rothschild
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14h00-16h00
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Clotting inhibitors, antithrombin III, protein C, protein S and protease inhibitors
|
Dr. M.H. Horellou
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16h00-18h00
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Other plasma derivatives : fibrin glue, rVIIa (Factor VII activated) ...
|
Dr. M.H. Horellou
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TOP
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|
Feb. 25, 2011
|
Vigilances
Module 16 (M16)
CTT/DESC/DUTS/DUQSPS
|
|
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09h00-13h00
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Haemovigilance from the blood donor to the labile blood product recipient: adverse
reactions and transfusion chain incidents
|
Dr. F Ferrer-Le Coeur
|
|
14h00-15h00
|
Pharmacovigilance
|
Dr. J. Berthou
|
|
15h00-16h00
|
Materiovigilance
|
Dr. C. Fretz
|
|
16h00-18h00
|
Reactovigilance & Biovigilance
|
Dr. B.N. Pham
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|
TOP
|
|
March 4, 2011
|
Transfusion Medicine (1)
Module 17 (M17)
CTT/DESC/DUTS/DUQSPS
|
|
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|
Transfusion of red cell concentrates
|
|
|
09h00-11h00
|
Hemoglobinopathies
|
Prof. F. Galacteros
|
|
11h00-13h00
|
Other haematological indications
|
Dr. B. Boval
|
|
15h00-16h00
|
Paediatric indications
|
Dr. D. Boyeldieu
|
|
16h00-18h00
|
Other non-haematological indications
|
Prof. A. Lienhart
|
|
TOP
|
|
March 11, 2011
|
Transfusion Medicine (2)
Module 18 (M18)
CTT/DESC/DUTS/DUQSPS
|
|
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|
Transfusion of platelet concentrates
|
|
|
09h00-11h00
|
Indications of platelet concentrates
|
Dr. G. Andreu
|
|
11h00-13h00
|
Transfusion indications of transplanted patients and patients with chimiotherapy
|
Dr. F. Lefrère
|
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Transfusion therapeutics
|
|
|
14h00-16h00
|
Platelet immunology and fetal and neonatal thrombopaenia
|
Dr. C. Kaplan
|
|
16h00-18h00
|
Substitutes to labile blood products
|
Prof. J.L. Wautier
|
|
TOP
|
|
March 18, 2011
|
Transfusion Medicine (3)
Module 19 (M19) (suite)
CTT/DESC/DUTS/DUQSPS
|
|
|
|
Transfusion therapeutics
|
|
|
09h00-10h30
|
Erythropoietin : fundamentals
|
Prof. N. Casadevall
|
|
10h30-12h30
|
Erythropoietin & priority blood sparing Per- and postsurgical blood retrieval Blood
waste calculations
|
Dr. M. Rossignol
|
|
14h00-15h30
|
Non-pharmacological blood sparing techniques
|
Prof. M. Samama
|
|
15h30-18h00
|
Normovolemic haemodilutions: useful or not ?
Massive transfusion
Transfusion in surgery & synthesis
|
Prof. Y. Ozier
|
|
TOP
|
|
March 23, 2011
|
Histocompatibility (1)
Module 20 (M20)
CTT/DESC/DUTS/DUQSPS
|
|
|
|
Histocompatibility - Transplantations
|
|
|
09h00-13h00
|
From the gene to the molecule. MHS (Major Histocompatibility System) function
|
L. Hallé
|
|
14h00-15h30
|
Antibody investigation and identification, cross match. Searching for compatible
donors with the single antigen techniques.
|
L. Absi
|
|
15h30-17h30
|
Transplantation-oriented blood typing : technique options, selection of the best
donor
|
K. Gagne
|
|
TOP
|
|
April 1, 2011
|
Histocompatibility (2)
Module 21 (M21)
CTT/DESC/DUTS/DUQSPS
|
|
|
09h00-10h30
|
Mechanisms controlling the immune response in hematopoietic stem cell transplantations
|
Prof. A. Buzyn
|
|
10h30-12h30
|
Mechanisms controlling the immune response in organ transplantations
|
Dr. A. Devys
|
|
14h00-17h00
|
What is the role of non classical HLA molecules in innate and adaptive immunity
?
|
Dr. C. Retière
|
|
TOP
|
|
April 8, 2011
|
Biotechnologies
Module 22 (M22)
DESC/DUTS/DUQSPS
|
|
|
09h00-13h00
|
Blood transfusion-related molecular biology
|
Dr. J.P. Cartron
|
|
14h00-16h30
|
Biological diagnosis-related molecular biology
|
Prof. M. Delpech
|
|
16h30-17h30
|
Biotechnology-derived components and reagents
|
Prof. Ph. Rouger
|
|
TOP
|
|
April 15, 2011
|
Cell and tissue therapies (1)
Module 23 (M23)
CTT/DESC/DUTS/DUQSPS
|
|
|
09h00-11h00
|
Cell therapy : technology – regulations
|
Dr. P. Bourin
|
|
11h00-12h30
|
Hematopoietic stem cell transplantation (treatment or ex-vivo expansion included
: techniques and indications)
|
Dr. H. Rouard
|
|
12h30-13h30
|
Specificities of placenta blood transplantation
|
Dr. R. Traineau
|
|
14h30-16h00
|
Production of mature red cells in vitro
|
Pr L. Douay
|
|
16h00-18h00
|
GVH - GVL – residual disease: biology and clinic
|
Pr J.P. Vernant
|
|
TOP
|
|
April 22, 2011
|
Cell and tissue therapies (2), cytokines and blood transfusion, synthesis of transfusion-related
adverse reactions
Module 24 (M24)
CTT/DESC/DUTS
|
|
|
09h00-11h00
|
Organ and tissue transplantations in France
|
Dr. M. Thuong
|
|
11h00-13h00
|
Cytokines and transfusion (other than erythropoietin)
|
Prof. O. Garraud
|
|
14h00-18h00
|
Immediate adverse reactions in recipients - synthesis : hemolytic accident, non
hemolytic fever, allergy, overload, TRALI, post-transfusion purpura, GVH
|
Dr. G. Andreu
|
|
TOP
|
|
April 29, 2011
|
Administration and finance management in blood transfusion establishments
Module 25 (M25)
CTT/DESC/DUTS
|
|
|
09h00–10h30
|
Liability in blood transfusion
|
Dr. V. Van Huffel
|
|
10h30-12h00
|
AFSSAPS (French agency for health product safety - inspections)
|
C. Guiol
|
|
13h30-14h30
|
Administration of a regional French Blood Establishment
|
K. Pitoy
|
|
14h30-16h00
|
Management of a regional French Blood Establishment
|
K. Pitoy
|
|
TOP
|
D3T :
Blood repository option : 14 – 18 Feb. 2011
Haemovigilance option : 21 to 25 Feb. 2011
|